Cefizox in plastic container
Cefizox in plastic container - General Information
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Pharmacology of Cefizox in plastic container
Cefizox in plastic container is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Cefizox in plastic container for patients
Cefizox in plastic container Interactions
Although the occurrence has not been reported with Cefizox, nephrotoxicity has been reported following concomitant administration of other cephalosporins and aminoglycosides.
Cefizox in plastic container Contraindications
Cefizox (ceftizoxime for injection, USP) is contraindicated in patients who have known allergy to the drug.
Additional information about Cefizox in plastic container
Cefizox in plastic container Indication: For the treatment of infections due to susceptible strains of microorganisms.
Mechanism Of Action: Cefizox in plastic container is an aminothiazolyl cephalosporin with an extended spectrum of activity against many gram-negative, nosocomially acquired pathogens. It has excellent beta-lactamase stability, with good in vitro activity against Haemophilus influenzae, Neisseria gonorrhoeae and Klebsiella pneumoniae. Cefizox in plastic container, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that ceftizoxime interferes with an autolysin inhibitor.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Ceftizoxime
Synonyms: Ceftizoxima [inn-spanish]; Ceftizoximum [inn-latin]
Drug Category: Cephalosporins; Anti-Bacterial Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Ceftizoxime: Cefizox; Cefizox in plastic container; Ceftix; Epocelin; Eposerin;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: 30% protein bound
Biotransformation: Ceftizoxime is not metabolized, and is excreted virtually unchanged by the kidneys in 24 hours.
Half Life: Not Available
Dosage Forms of Cefizox in plastic container: Solution Intravenous
Tablet Rectal
Chemical IUPAC Name: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula: C13H13N5O5S2
Ceftizoxime on Wikipedia: https://en.wikipedia.org/wiki/Ceftizoxime
Organisms Affected: Enteric bacteria and other eubacteria
